In this Dutch-language factsheet, we give an overview of effective elements of mentoring of youth, based on scientific literature and experiential knowledge. Mentoring is a form of personal guidance in which mentor and mentee have a one-on-one relationship, where the development of the mentee is the focus. Mentoring seems to have positive effects on for example presence and a better attitude at school, less alcohol and drugs use, and less delinquent behavior. Building a trusting relationship between mentor and mentee is crucial. This factsheet is made by the Erasmus Urban Youth Lab. This is an initiative of the Erasmus University Rotterdam, the Erasmus Medical Centre Rotterdam, and research institute IVO. In the research project ‘Vulnerable Youth in Major Cities’ we examine, among others, the effectiveness of and experiences with mentoring.